Tablet Disintegrant
Fast breakup of compressed tablets in water, even at high compression force.
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Chelora Chemicals UAE supplies Croscarmellose Sodium (CAS 74811-65-7), the cross-linked superdisintegrant, to tablet and capsule manufacturers, nutraceutical and veterinary formulators and contract packers across Dubai, Abu Dhabi, Sharjah and all seven Emirates, with batch-wise COA, moisture-protected packing and fast GCC delivery.
Croscarmellose Sodium is the internally cross-linked sodium salt of carboxymethylcellulose, supplied as a white to greyish-white, free-flowing powder. It does not dissolve in water but swells rapidly and wicks moisture into the tablet core, which is why it is one of the most widely used superdisintegrants in oral solid dosage forms. In food use it is known as E468.
Typical uses are as a tablet disintegrant at roughly 0.5–5% w/w in direct-compression and wet-granulation formulas, as a disintegrant in hard capsule fills, in chewable and nutraceutical tablets and in veterinary tablets. Its fibrous structure keeps working even when tablets are compressed to high hardness.
As an established chemical supplier in the UAE, Chelora Chemicals sources Croscarmellose Sodium from approved manufacturers with consistent degree of substitution, swelling behaviour and low sodium chloride and sodium glycolate residues, and delivers it to customers in Dubai, Abu Dhabi, Sharjah, Ajman, Ras Al Khaimah, Fujairah and Umm Al Quwain, as well as export customers in Saudi Arabia, Oman, Qatar, Kuwait, Bahrain, Africa and South Asia.
Typical specification and physical data for Croscarmellose Sodium supplied in the UAE. Batch-specific values are always confirmed on the Certificate of Analysis issued with each lot.
| Parameter | Specification |
|---|---|
| Appearance | White to greyish-white, free-flowing powder |
| Identification | Conforms (IR and swelling tests) |
| pH (1% dispersion) | 5.0 – 7.0 |
| Loss on drying | Not more than 10.0% |
| Water-soluble substances | Not more than 10.0% |
| Sodium chloride + sodium glycolate | Not more than 0.5% (sum) |
| Grade | Pharmacopoeial (USP-NF / Ph. Eur. / BP / IP) as per COA |
| Packing & documents | 20–25 kg lined bags / drums; COA, SDS, TDS, COO |
| Property | Value |
|---|---|
| Chemical name | Cross-linked sodium carboxymethylcellulose |
| CAS number | 74811-65-7 |
| Repeating unit | C₈H₁₁NaO₇ (approx., at full substitution) |
| Molecular weight | Polymer (cross-linked, insoluble) |
| Physical state (20 °C) | Solid powder |
| Solubility | Insoluble in water; swells to several times its volume |
| Melting point | Does not melt; chars above approx. 225 °C |
| Sensitivity | Hygroscopic; stable under normal storage; keep dry and tightly sealed |
Values are typical literature data for reference only and do not form a sales specification. Contact us for the latest TDS and batch COA.
Need a specific particle-size profile, degree of substitution or sodium glycolate limit? We match your spec to approved makers.
Share Your Specification →From direct-compression tablets to nutraceutical capsules, Croscarmellose Sodium is a workhorse disintegrant for UAE and GCC formulators.
Fast breakup of compressed tablets in water, even at high compression force.
Used intra- and extra-granularly to balance disintegration and dissolution.
Helps powder blends in hard capsules disperse quickly once the shell opens.
Keeps vitamin, mineral and herbal tablets disintegrating within label limits.
Supports quick release in animal-health tablets and boluses.
Small lots for laboratories tuning disintegration time and dissolution profile.
Our UAE customers for Croscarmellose Sodium range from tablet plants in the free zones to regional traders re-exporting through Jebel Ali.
Generic and branded oral solid dosage plants.
Vitamin, mineral and herbal products.
CMOs running multi-client tableting campaigns.
Animal-health tablets and boluses.
Dubai and Sharjah traders re-exporting to the GCC, Africa and South Asia.
Supplement brands outsourcing to local packers.
Formulation labs needing small lots with full documentation.
Importers in Saudi Arabia, Oman, Qatar, Kuwait, Bahrain and Africa buying via UAE.
We supply Croscarmellose Sodium to industrial areas, ports and free zones throughout the UAE, with re-export to the wider GCC and beyond.
Fast local delivery to tablet and capsule manufacturers in Dubai, plus re-export via Jebel Ali Port.
Supply to tablet and capsule manufacturers in Musaffah, KEZAD and around Khalifa Port.
Serving tablet and capsule manufacturers across Sharjah's industrial areas and free zones.
Reliable deliveries for Ajman-based tablet and capsule manufacturers from our UAE stock and import programme.
Supplying tablet and capsule manufacturers in RAK's free zones and ports.
Road delivery to the east coast with access to Port of Fujairah for regional shipments.
Consolidated with our northern Emirates deliveries for factories and traders.
Export from the UAE on EXW, FOB, CFR, CIF, DAP or DDP terms.
Croscarmellose Sodium is hygroscopic and loses flow and swelling performance when it absorbs moisture, so we ship it in sealed polyethylene-lined packs suited to UAE summer heat and humidity.
Whether you need a few bags for a pilot batch or regular loads for continuous tableting, we plan packing, labelling and transport from port or warehouse to your gate.
20–25 kg double-lined bags and fibre drums.
1–5 kg packs for lab trials and formulation work.
Stretch-wrapped pallets for regular production runs.
EXW UAE, FOB Jebel Ali / Khalifa, CFR, CIF, DAP, DDP.
A simple, transparent procurement process built for busy purchase teams.
Send product name, CAS 74811-65-7, grade (USP-NF / Ph. Eur.), quantity, packing and delivery Emirate.
We match approved makers and send a quotation with packing, Incoterm and lead time.
COA, SDS and TDS shared upfront, with Croscarmellose Sodium samples available for qualification.
We lock in the batch, arrange sealed packing and GHS labelling.
Customs clearance, documentation and transport and transport from port or warehouse.
Delivery to your site in the UAE or GCC, plus repeat-order planning.
Every lot of Croscarmellose Sodium we supply is traceable to its manufacturer and production date. We check pH, loss on drying and residue limits against your requirement before dispatch so the disintegration performance of your tablets is not put at risk by off-spec material.
Low-hazard excipient. Croscarmellose Sodium is not classified as hazardous, but as a fine organic powder it can form combustible dust clouds and may irritate the eyes and respiratory tract. Always refer to the supplied SDS for the classification of the grade supplied.
Approved makers with a controlled degree of substitution keep disintegration time consistent from batch to batch.
Clear quotes with grade, packing, Incoterm and lead time so your purchase team can decide quickly.
We understand the pharmacopoeial tests tablet makers actually check on Croscarmellose Sodium.
COA, SDS, TDS, COO and DG paperwork ready for audits, customs and GCC export.
Delivery of Croscarmellose Sodium across the seven Emirates and export to Saudi Arabia, Oman, Qatar, Kuwait and Bahrain.
From sample and trial lots to annual supply contracts and bulk programmes.
Common questions from UAE and GCC buyers about Croscarmellose Sodium supply, specifications and delivery.
Croscarmellose Sodium is used mainly as a superdisintegrant in tablets and capsules, typically at about 0.5–5% w/w. It is also used in chewable and nutraceutical tablets and in veterinary dosage forms.
The CAS number of Croscarmellose Sodium is 74811-65-7. Its molecular formula is (C₈H₁₁NaO₇)ₙ and its molecular weight is Polymer (cross-linked, insoluble).
Croscarmellose Sodium (CAS 74811-65-7) is also sold as Croscarmellose Na, cross-linked CMC-Na, internally cross-linked sodium carboxymethylcellulose, E468. Please mention the CAS number in your enquiry so we quote the right material.
Chelora Chemicals UAE is a B2B chemical supplier and distributor of Croscarmellose Sodium, serving Dubai, Abu Dhabi, Sharjah, Ajman, Ras Al Khaimah, Fujairah and Umm Al Quwain, with full COA, SDS and TDS documentation and export to the wider GCC.
Yes. We deliver to all seven Emirates, including Jebel Ali and JAFZA in Dubai, KEZAD, Musaffah and Khalifa Port in Abu Dhabi, and SAIF Zone and Hamriyah Free Zone in Sharjah, as well as RAKEZ, Ajman Free Zone and Fujairah.
We supply pharmaceutical-grade Croscarmellose Sodium to USP-NF, Ph. Eur., BP and IP standards, as stated on the COA. Particle-size and degree-of-substitution requirements can be matched on request.
Croscarmellose Sodium (CAS 74811-65-7) is the cross-linked, water-insoluble form of carboxymethylcellulose. It is different from sodium carboxymethylcellulose (CMC, which dissolves and is used as a thickener and binder) and from other superdisintegrants such as sodium starch glycolate and crospovidone.
Share the grade (USP-NF / Ph. Eur.), quantity, packing, Incoterm and delivery Emirate through our contact page and our team aims to respond within one business day.
Typically 20–25 kg polyethylene-lined bags or fibre drums, with smaller packs for trials. Packs are sealed against moisture and labelled for safe transport.
The minimum order depends on packing and current stock. We handle everything from a few bags or small packs for trials and lab qualification up to full container loads.
Store in tightly closed, lined bags or drums in a cool, dry, well-ventilated area away from direct sun. Reseal opened packs promptly, as the powder is hygroscopic.
Croscarmellose Sodium is not classified as hazardous, but like any fine organic powder it can form combustible dust clouds and irritate eyes and airways. Use dust control and follow the SDS.
Yes. We export from the UAE to Saudi Arabia, Oman, Qatar, Kuwait, Bahrain, East and West Africa, South Asia and other markets on EXW, FOB, CFR, CIF, DAP or DDP terms, subject to the import rules of each destination.
Yes. Samples are available for qualification on request, together with the COA and SDS, so your QC or R&D team can approve the material before a commercial order.
Typical use levels are about 0.5–5% w/w, commonly around 2% in direct compression and 3% in wet granulation. The optimum depends on your API, tablet hardness and dissolution target, so confirm with your own trials.
No. It is insoluble in water but swells rapidly to several times its volume, and that swelling is what breaks the tablet apart.
Tell us your grade (USP-NF / Ph. Eur.), quantity, packing and delivery Emirate, and get a quote for Croscarmellose Sodium from a trusted chemical supplier in the UAE.